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Medications With Possible Side Effects: T-Z
Brand name Generic name Indication Reported Ocular Side Effects
Tagamet cimetidine ulcers Uncommon, but can include transient myopia, perception of yellow or pink tinge to objects, and dry eye symptoms. There have been isolated reports of angle closure glaucoma and visual hallucinations.
Tegretol carbamazepine epilepsy Diplopia, blurry vision, a "heavy feeling in the eyes." Effects are most common when dosage exceeds 1.2g. About a fourth of all patients develop neurologic or hematopoietic reactions; the former can lead to ocular effects such as downbeat nystagmus.
Tenormin/Tenoretic atenolol hyperten-sion, angina, myocardial infarction Beta blockers can cause visual disturbances and vivid hallucinations and increase migrainous scotomata. They can worsen myasthenia gravis and occasionally cause extraocular paresis and diplopia. They can decrease tear secretion.
Toprol XL metoprolol succinate hyperten-sion, angina This is a new drug, but other beta blockers have caused visual disturbances and vivid hallucinations, worsened myasthenia gravis, decreased tear secretion and decreased intraocular pressure.
Transderm-nitro nitroglycerin angina Uncommon. Theoretically has potential to precipitate angle-closure glaucoma.
Unasyn ampicillin, sulbactam infection May cause allergic skin reactions and unmask or aggravate the symptoms of myasthenia gravis.
Vasotec/ Vaseretic enalapril hyperten-sion, heart failure, left ventricular dysfunction Rare, seldom clinically significant. The most common side effect may be angioneurotic edema around the eyes, typically occurring within three weeks after starting the drug. All reactions are reversible with discontinued drug use.
Ventolin albuterol sulfate asthma Seldom clinically significant. Rarely, patients may experience vivid hallucinations.
Versed midazolam anesthesia Side effects from benzodiazepine derivatives are rare, but the drugs can cause decreased corneal reflex, decreased depth perception and abnormal extraocular muscle movement. Can cause a temporary allergic conjunctivitis and may cause pupillary dilatation leading to the isolated narrow-angle attack.
Xanax alprazolam anxiety Side effects from benzodiazepine derivatives are rare, but the drugs can cause decreased corneal reflex, decreased depth perception and abnormal extraocular muscle movement. Can cause a temporary allergic conjunctivitis and may cause pupillary dilatation leading to the isolated narrow-angle attack.
Zantac rantidine ulcers Uncommon; typically occur only in young children or severely ill elderly patients. Can include decreased vision, erythema, conjunctivitis, angioneurotic edema and urticaria of the lids and conjunctiva, hallucinations, color vision defects and subconjunctival or retinal hemorrhages secondary to drug-induced anemia
Zovirax acyclovir herpes Rare. May cause periocular edema. May increase ocular irritation in keratoconjunctivitis sicca patients.

Medications with
possible side effects
:
A-I
K-S
T-Z

Medications with
no side effects
:
Top 100

Additional Resources

New York Glaucoma
Research Institute

310 East 14th St.
New York, NY 10003
(212) 477-7540

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